Pre Formulation
Our dedicated team of scientists have their core training in the area of preformulation and have expertise in the complete pharmaceutical profiling of molecules Preformulation Services:
- Polymorph screening and selection
- Salt form selection
- Crystalline properties
- pH solubility and stability
- Solid-state and solution-state stability
- Photostability
- pKa and partition coefficient determination
- Hygroscopicity
- Morphology assessment
- Solubility studies
- Intrinsic dissolution
- Excipient compatibility
- Leachables and Extractables studies
- Flowability
- Particle size determination by laser lights
- Container – active pharmaceutical ingredient (API) interactions
Capabilities:
- Thermal analysis: DSC (Differential Scanning Calorimetry), TGA (Thermogravimetric Analyzer)
- Dynamic Vapor sorption/desorption
- pXRD (X-Ray Diffraction)
- FT-IR (A Fourier Transform Infrared) spectrometer Capillary Electrophoresis
- SEM (Scanning Electron Microscopy) and TEM (Transmission Electron Microscope)
- Potentiometer
- Hot-stage Microscopy
- Laser light diffraction Particle size analyzer
- Intrinsic dissolution
- Head Space GC analyzer
- ICPMS (Inductively Coupled Plasma Mass Spectrometry)
- IC (Ion Chromatography)
- Zeta sizer
- Malvern particle size analyzer
- AAS (Atomic Absorption Spectroscopy)